Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gnrh1  gonadotropin releasing hormone 1   (Synonyms: LHRH, LNRH)
Results	Reference
1	J:175836 Cariboni A, Davidson K, Dozio E, Memi F, Schwarz Q, Stossi F, Parnavelas JG, Ruhrberg C, VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Development. 2011 Sep;138(17):3723-33
1*	J:47986 Dellovade TL, Pfaff DW, Schwanzel-Fukuda M, The gonadotropin-releasing hormone system does not develop in Small-Eye (Sey) mouse phenotype. Brain Res Dev Brain Res. 1998 May 15;107(2):233-40
1	J:168231 Forni PE, Fornaro M, Guenette S, Wray S, A role for FE65 in controlling GnRH-1 neurogenesis. J Neurosci. 2011 Jan 12;31(2):480-91
1	J:83684 Heger S, Seney M, Bless E, Schwarting GA, Bilger M, Mungenast A, Ojeda SR, Tobet SA, Overexpression of glutamic acid decarboxylase-67 (GAD-67) in gonadotropin-releasing hormone neurons disrupts migratory fate and female reproductive function in mice. Endocrinology. 2003 Jun;144(6):2566-79
1	J:231756 Hoffmann HM, Trang C, Gong P, Kimura I, Pandolfi EC, Mellon PL, Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility. J Neurosci. 2016 Mar 23;36(12):3506-18
1*	J:261765 Knoll JG, Clay CM, Bouma GJ, Henion TR, Schwarting GA, Millar RP, Tobet SA, Developmental profile and sexually dimorphic expression of kiss1 and kiss1r in the fetal mouse brain. Front Endocrinol (Lausanne). 2013;4:140
1*	J:63183 Kramer PR, Guerrero G, Krishnamurthy R, Mitchell PJ, Wray S, Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha. Mech Dev. 2000 Jun;94(1-2):79-94
1*	J:61910 Kramer PR, Krishnamurthy R, Mitchell PJ, Wray S, Transcription factor activator protein-2 is required for continued luteinizing hormone-releasing hormone expression in the forebrain of developing mice. Endocrinology. 2000 May;141(5):1823-38
1	J:177773 Messina A, Ferraris N, Wray S, Cagnoni G, Donohue DE, Casoni F, Kramer PR, Derijck AA, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P, Dysregulation of Semaphorin7A/beta1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility. Hum Mol Genet. 2011 Dec 15;20(24):4759-74
1	J:168181 Metz H, Wray S, Use of mutant mouse lines to investigate origin of gonadotropin-releasing hormone-1 neurons: lineage independent of the adenohypophysis. Endocrinology. 2010 Feb;151(2):766-73
1*	J:279114 Pandolfi EC, Tonsfeldt KJ, Hoffmann HM, Mellon PL, Deletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting in Infertility. Endocrinology. 2019 Sep 1;160(9):2151-2164
1	J:276971 Saadi H, Shan Y, Marazziti D, Wray S, GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice. Front Cell Neurosci. 2019;13:200
1	J:109381 Schwarting GA, Kostek C, Bless EP, Ahmad N, Tobet SA, Deleted in colorectal cancer (DCC) regulates the migration of luteinizing hormone-releasing hormone neurons to the basal forebrain. J Neurosci. 2001 Feb 1;21(3):911-9
1	J:89800 Schwarting GA, Raitcheva D, Bless EP, Ackerman SL, Tobet S, Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons. Eur J Neurosci. 2004 Jan;19(1):11-20
1	J:301210 Taroc EZM, Katreddi RR, Forni PE, Identifying Isl1 Genetic Lineage in the Developing Olfactory System and in GnRH-1 Neurons. Front Physiol. 2020;11:601923
1*	J:276901 Taroc EZM, Lin JM, Tulloch AJ, Jaworski A, Forni PE, GnRH-1 Neural Migration From the Nose to the Brain Is Independent From Slit2, Robo3 and NELL2 Signaling. Front Cell Neurosci. 2019;13:70
1	J:283398 Taroc EZM, Naik AS, Lin JM, Peterson NB, Keefe DL Jr, Genis E, Fuchs G, Balasubramanian R, Forni PE, Gli3 Regulates Vomeronasal Neurogenesis, Olfactory Ensheathing Cell Formation, and GnRH-1 Neuronal Migration. J Neurosci. 2020 Jan 8;40(2):311-326
1	J:245068 Taroc EZM, Prasad A, Lin JM, Forni PE, The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs. Biol Open. 2017 Oct 15;6(10):1552-1568
1*	J:125764 Tiong J, Locastro T, Wray S, Gonadotropin-releasing hormone-1 (GnRH-1) is involved in tooth maturation and biomineralization. Dev Dyn. 2007 Nov;236(11):2980-92
1	J:242190 Vastagh C, Schwirtlich M, Kwakowsky A, Erdelyi F, Margolis FL, Yanagawa Y, Katarova Z, Szabo G, The spatiotemporal segregation of GAD forms defines distinct GABA signaling functions in the developing mouse olfactory system and provides novel insights into the origin and migration of GnRH neurons. Dev Neurobiol. 2015 Mar;75(3):249-70